Hewlett-Packard 4 Series Manual

A SERVICE OF

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Appendix B Overview of Isotopes

B-6 Applied Biosystems

B

B.2 Monoisotopic

and Average Masses

When isotopes are clearly resolved (Figure B-6), the

monoisotopic mass is used for mass labeling, and

corresponds to the lowest mass peak in the cluster.

Figure B-6 Monoisotopic Mass

When isotopes are not resolved (Figure B-7), the average

mass is used for mass labeling, and corresponds to the

centroid of the unresolved peak cluster (weighted average of

all isotope peaks in the cluster).

Monoisotopic mass

corresponds to

lowest mass peak